Hyperkalemia is a common life-threatening condition causing severe electrophysiologic derangements and arrhythmias. The beneficial effects of calcium (Ca2+) treatment for hyperkalemia have been attributed to "membrane stabilization," by restoration of resting membrane potential (RMP). However, the underlying mechanisms remain poorly understood. Our objective was to investigate the mechanisms underlying adverse electrophysiologic effects of hyperkalemia and the therapeutic effects of Ca2+ treatment.

中文翻译：

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钙治疗高钾血症的有益效果并非由于“膜稳定”。


高钾血症是一种常见的危及生命的疾病，会导致严重的电生理紊乱和心律失常。钙 (Ca2+) 治疗高钾血症的有益效果归因于通过恢复静息膜电位 (RMP) 来实现“膜稳定”。然而，其根本机制仍然知之甚少。我们的目的是研究高钾血症不良电生理效应的机制以及 Ca2+ 治疗的治疗效果。