当前位置：
X-MOL 学术
›
Ann. N. Y. Acad. Sci.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Androgen abuse: Risks and adverse effects in men
Annals of the New York Academy of Sciences ( IF 4.1 ) Pub Date : 2024-07-23 , DOI: 10.1111/nyas.15187 Bonnie Grant 1 , Elizabeth Hyams 1 , Rhianna Davies 1 , Suks Minhas 2 , Channa N Jayasena 1
Annals of the New York Academy of Sciences ( IF 4.1 ) Pub Date : 2024-07-23 , DOI: 10.1111/nyas.15187 Bonnie Grant 1 , Elizabeth Hyams 1 , Rhianna Davies 1 , Suks Minhas 2 , Channa N Jayasena 1
Affiliation
|
Androgens, formerly known as anabolic-androgenic steroids, mimic the effects of testosterone and are being increasingly abused for nonmedical purposes such as body and performance enhancement. Androgen abuse is associated with increased mortality, and multisystem adverse effects have been reported, including cardiovascular toxicity, infertility, hypogonadism, hepatotoxicity, and mental health disorders. Men may present with the negative health consequences of androgen abuse even despite cessation for a number of years. There is frequently a reluctance to disclose androgen abuse, and substances are often sourced from the black market, which is not regulated and where the products sold may be counterfeit. All men should be encouraged to stop androgen abuse. Managing associated adverse effects will be organ-specific and is complex due to physical and neuropsychiatric symptoms, substance dependence, and high rates of relapse. Given the broad reach and prolonged adverse effects of androgen abuse, clinicians across medical specialties should have an awareness of androgen abuse, its increasing prevalence, and the harms it poses to men and their families. This narrative review aims to summarize the adverse effects and risks associated with androgen abuse.
中文翻译：
雄激素滥用：男性的风险和不良影响
雄激素以前称为合成代谢雄激素类固醇，模仿睾酮的作用，并且越来越多地被滥用于非医疗目的，例如增强身体和性能。雄激素滥用与死亡率增加有关，并且已报道多系统不良反应，包括心血管毒性、不孕症、性腺功能减退症、肝毒性和精神健康障碍。即使男性已停止雄激素多年，也可能会因滥用雄激素而对健康产生负面影响。人们常常不愿披露雄激素滥用情况，而且这些物质往往来自黑市，黑市不受监管，而且销售的产品可能是假冒的。应鼓励所有男性停止滥用雄激素。由于身体和神经精神症状、物质依赖性和高复发率，相关不良反应的管理将是针对器官的，并且很复杂。鉴于雄激素滥用的广泛影响和长期不良影响，各医学专业的临床医生应该认识到雄激素滥用、其日益普遍的现象及其对男性及其家庭造成的危害。本叙述性综述旨在总结与雄激素滥用相关的不利影响和风险。
更新日期：2024-07-23
中文翻译：
雄激素滥用：男性的风险和不良影响
雄激素以前称为合成代谢雄激素类固醇，模仿睾酮的作用，并且越来越多地被滥用于非医疗目的，例如增强身体和性能。雄激素滥用与死亡率增加有关，并且已报道多系统不良反应，包括心血管毒性、不孕症、性腺功能减退症、肝毒性和精神健康障碍。即使男性已停止雄激素多年，也可能会因滥用雄激素而对健康产生负面影响。人们常常不愿披露雄激素滥用情况，而且这些物质往往来自黑市，黑市不受监管，而且销售的产品可能是假冒的。应鼓励所有男性停止滥用雄激素。由于身体和神经精神症状、物质依赖性和高复发率，相关不良反应的管理将是针对器官的，并且很复杂。鉴于雄激素滥用的广泛影响和长期不良影响，各医学专业的临床医生应该认识到雄激素滥用、其日益普遍的现象及其对男性及其家庭造成的危害。本叙述性综述旨在总结与雄激素滥用相关的不利影响和风险。
京公网安备 11010802027423号