Nitro compounds are important intermediates in medicine, agrochemicals, dyes and polymers. In recent years, the use of tert-butyl nitrite (t-BuONO) has attracted great attention and made promising progress. Currently, there is no review that specifically discusses the use of t-BuONO for the synthesis of nitro compounds via a C-H bond radical strategy. Therefore, this review aims to focus on the recent progress of using t-BuONO as a nitration reagent according to the type of reaction substrate, especially to focus on the discussion of reaction mechanism in representative cascade reactions to provide insights for the development prospects of tert-butyl nitrite.

中文翻译：

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亚硝酸叔丁酯作为有机合成中 C-H 键（亚）硝化反应的特权试剂


硝基化合物是医药、农用化学品、染料和聚合物的重要中间体。近年来，亚硝酸叔丁酯（t-BuONO）的使用引起了高度关注并取得了可喜的进展。目前，还没有专门讨论使用 t-BuONO 通过 C-H 键自由基策略合成硝基化合物的综述。因此，本文旨在根据反应底物类型，重点介绍叔丁醇作为硝化试剂的最新进展，特别是重点讨论代表性级联反应中的反应机理，为叔丁醇的发展前景提供参考。亚硝酸丁酯。