<br>当前微胶囊设计和微胶囊化工艺面临的挑战：综述,ACS Applied Materials & Interfaces

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当前微胶囊设计和微胶囊化工艺面临的挑战：综述
ACS Applied Materials & Interfaces ( IF 8.3 ) Pub Date : 2024-07-23 , DOI: 10.1021/acsami.4c02462
Benjamin T Lobel ₁ , Daniele Baiocco ₂ , Mohammed Al-Sharabi ₃ , Alexander F Routh ₃ , Zhibing Zhang ₂ , Olivier J Cayre ₁

Affiliation

微胶囊化是一种先进的方法，用于保护、保存和/或输送多种工业领域的活性材料，例如药品、化妆品、香料、油漆、涂料、洗涤剂、食品和农用化学品。聚合物材料已被广泛用作微胶囊壳，以提供适当的阻隔性能，以实现封装的活性成分的受控释放。然而，此类胶囊存在显着的局限性，包括不期望的浸出和通常使用的聚合物的不可生物降解的性质。此外，制造微胶囊的能源成本是设计微胶囊系统和相应生产工艺时需要考虑的重要因素。最近与联合国可持续发展目标相关的因素正在改变此类微胶囊系统的设计方式，以追求高效、安全、具有成本效益和环境友好的“理想”微胶囊。本综述概述了微胶囊的进展，重点是可持续的微胶囊设计。还描述了评估微胶囊生物降解性的关键评估技术，符合最近不断发展的欧盟要求。此外，最常见的微胶囊制造方法是在其能源需求的框架内提出的。最近有前景的微胶囊设计还因其适合满足当前的设计要求和严格的法规、应对持续的挑战、限制和机遇而受到关注。

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Current Challenges in Microcapsule Designs and Microencapsulation Processes: A Review

Microencapsulation is an advanced methodology for the protection, preservation, and/or delivery of active materials in a wide range of industrial sectors, such as pharmaceuticals, cosmetics, fragrances, paints, coatings, detergents, food products, and agrochemicals. Polymeric materials have been extensively used as microcapsule shells to provide appropriate barrier properties to achieve controlled release of the encapsulated active ingredient. However, significant limitations are associated with such capsules, including undesired leaching and the nonbiodegradable nature of the typically used polymers. In addition, the energy cost of manufacturing microcapsules is an important factor to be considered when designing microcapsule systems and the corresponding production processes. Recent factors linked to UN sustainability goals are modifying how such microencapsulation systems should be designed in pursuit of “ideal” microcapsules that are efficient, safe, cost-effective and environmentally friendly. This review provides an overview of advances in microencapsulation, with emphasis on sustainable microcapsule designs. The key evaluation techniques to assess the biodegradability of microcapsules, in compliance with recently evolving European Union requirements, are also described. Moreover, the most common methodologies for the fabrication of microcapsules are presented within the framework of their energy demand. Recent promising microcapsule designs are also highlighted for their suitability toward meeting current design requirements and stringent regulations, tackling the ongoing challenges, limitations, and opportunities.

更新日期：2024-07-23

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