Staphylococcus aureus (S. aureus) is a kind of pathogenic bacteria which can lead to food poisoning, hospital, and community infections. S. aureus and methicillin-resistant S. aureus (MRSA) have become headaches for public health worldwide. Therefore, strengthening the detection of S. aureus and MRSA is a critical step to prevent and control its spread and infection. This review summarized multiple detection methods (electrochemical, optical, and other biosensors) for sensitive and efficient detection of nonresistant and resistant S. aureus. First, we have introduced the principle and methods of detection platform for S. aureus and MRSA. We also contrasted various detection strategies. Finally, the current situation and prospect of S. aureus and MRSA detection in the future are explored in depth, and its development direction of detection methods is also predicted. In this review, we found that although biosensors have shown tremendous brilliance in the field of monitoring, they are currently in the experimental stage. It can be certain that we are very close to entering the commercialization stage. The point-of care testing available to nonprofessionals will become a new direction. We firmly believe that the monitoring system will be more perfect and stable and public life will be healthier and safer.

中文翻译：

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抓住隐藏的刺客：当前金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌的检测策略


金黄色葡萄球菌（S. aureus）是一种可导致食物中毒、医院和社区感染的致病菌。金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌（MRSA）已成为全球公共卫生的难题。因此，加强金黄色葡萄球菌和MRSA的检测是防控其传播和感染的关键一步。本综述总结了多种检测方法（电化学、光学和其他生物传感器），用于灵敏、高效地检测非耐药和耐药金黄色葡萄球菌。首先介绍了金黄色葡萄球菌和MRSA检测平台的原理和方法。我们还对比了各种检测策略。最后，深入探讨了金黄色葡萄球菌和MRSA检测的现状和前景，并预测了其检测方法的发展方向。在这篇综述中，我们发现虽然生物传感器在监测领域表现出了巨大的才华，但它们目前还处于实验阶段。可以肯定的是，我们已经非常接近进入商业化阶段。可供非专业人士使用的即时检测将成为一个新的方向。我们坚信，监控系统将更加完善、稳定，公众生活将更加健康、安全。