Enterovirus-A71 preferentially infects and replicates in human motor neurons, inducing neurodegeneration by ferroptosis,Emerging Microbes & Infections

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Enterovirus-A71 preferentially infects and replicates in human motor neurons, inducing neurodegeneration by ferroptosis
Emerging Microbes & Infections ( IF 8.4 ) Pub Date : 2024-07-25 , DOI: 10.1080/22221751.2024.2382235
Wai Hon Chooi ₁ , Winanto _{1,

2} , Yingying Zeng ₁ , Cheryl Yi-Pin Lee ₁ , Ze Qin Lim _{3,

4} , Pradeep Gautam ₁ , Justin Jang Hann Chu _{1,

3} , Yuin-Han Loh ₁ , Sylvie Alonso _{3,

4} , Shi-Yan Ng _{1,

5,

6}

Affiliation

Enterovirus A71 (EV-A71) causes Hand, Foot, and Mouth Disease and has been clinically associated with neurological complications. However, there is a lack of relevant models to elucidate the neurop...

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