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Symptom flares in women with chronic pelvic pain: Questionnaire study within a cohort study (translational research in pelvic pain (TRiPP))
BJOG: An International Journal of Obstetrics & Gynaecology ( IF 4.7 ) Pub Date : 2024-07-19 , DOI: 10.1111/1471-0528.17915
Lydia Coxon 1 , Celia Lugt 1 , Andrew W Horne 2 , Emma Evans 1 , Pedro Abreu-Mendes 3 , Lars Arendt-Nielsen 4, 5, 6 , Qasim Aziz 7 , Christian M Becker 1 , Judy Birch 8 , Ana Charrua 3 , Lysia Demetriou 1 , Joana Ferreira-Gomes 3 , Anja Hoffman 9 , Lone Hummelshoj 10 , Michal Krassowski 1 , Claire E Lunde 11, 12 , Jane Meijlink 13 , Stacey A Missmer 14, 15, 16, 17 , Danielle Perro 1 , Krina T Zondervan 1 , Christine B Sieberg 15, 18, 19 , Francisco Cruz 3 , Jens Nagel 20 , Katy Vincent 1
Affiliation  

ObjectiveTo quantify the variation, triggers and impact on quality of life of symptom flares in women with chronic pelvic pain (CPP).DesignCross‐sectional questionnaire within the Translational Research in Pelvic Pain clinical cohort study.SettingWomen with CPP, with subgroups of women with endometriosis (EAP), interstitial cystitis/bladder pain syndrome (BPS), comorbid endometriosis and interstitial cystitis/bladder pain syndrome (EABP), and those with pelvic pain without endometriosis or interstitial cystitis/bladder pain syndrome (PP).Population or SampleA total of 100 participants.MethodsDescriptive and comparative analysis from flares questionnaire.Main Outcome MeasuresThe prevalence, characteristics and triggers of short, medium and long symptom flares in CPP.ResultsWe received 100 responses of 104 questionnaires sent. Seventy‐six per cent of women with CPP have ever experienced symptom flares of at least one length (short, medium and/or long). Flares are associated with painful and non‐painful symptoms. There is large variation for the frequency, duration, symptoms and triggers for flares. Over 60% of participants reported flares as stopping them from doing things they would usually do, >80% reported thinking about symptoms of flares and >80% reported flares being bothersome.ConclusionsFlares are prevalent and clinically very important in CPP. More research is needed to elucidate the mechanisms and characteristics underlying flares. Clinical practice should include an enquiry into flares with the aim of finding strategies to lessen their burden.

中文翻译:


慢性盆腔疼痛女性的症状发作:队列研究中的问卷调查(盆腔疼痛转化研究 (TRiPP))



目的量化慢性盆腔疼痛 (CPP) 女性症状发作的变化、触发因素及其对生活质量的影响。设计盆腔疼痛转化研究临床队列研究中的横断面调查问卷。设置患有 CPP 的女性,以及患有子宫内膜异位症的女性亚组(EAP),间质性膀胱炎/膀胱疼痛综合征(BPS),共病子宫内膜异位症和间质性膀胱炎/膀胱疼痛综合征(EABP),以及有盆腔疼痛但不伴有子宫内膜异位症或间质性膀胱炎/膀胱疼痛综合征(PP)的患者。人群或样本总计100 名参与者。方法对突发症状问卷进行描述性和比较分析。主要结果指标 CPP 中短期、中期和长期症状突发的患病率、特征和触发因素。结果我们收到 104 份问卷,收到 100 份回复。 76% 的 CPP 女性曾经历过至少一种长度的症状发作(短、中和/或长)。耀斑与疼痛和非疼痛症状有关。耀斑的频率、持续时间、症状和触发因素存在很大差异。超过 60% 的参与者报告耀斑会阻止他们做他们通常会做的事情,>80% 的参与者报告考虑耀斑的症状,>80% 的参与者报告耀斑令人烦恼。 结论 耀斑在 CPP 中很普遍,并且在临床上非常重要。需要更多的研究来阐明耀斑的机制和特征。临床实践应包括对耀斑的调查,目的是找到减轻其负担的策略。
更新日期:2024-07-19
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