Outcomes of patients with alcohol-associated hepatitis and acute kidney injury – Results from the HRS Harmony Consortium,Alimentary Pharmacology & Therapeutics

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Outcomes of patients with alcohol-associated hepatitis and acute kidney injury – Results from the HRS Harmony Consortium
Alimentary Pharmacology & Therapeutics ( IF 6.6 ) Pub Date : 2024-07-15 , DOI: 10.1111/apt.18159
Ann T Ma ₁ , Andrew S Allegretti ₂ , Giuseppe Cullaro ₃ , Tianqui Ouyang ₂ , Sumeet K Asrani ₄ , Raymond T Chung ₅ , Eric M Przybyszewski ₅ , Robert M Wilechansky ₅ , Jevon E Robinson ₂ , Pratima Sharma ₆ , Douglas A Simonetto ₇ , Prasun Jalal ₈ , Eric S Orman ₉ , Hani M Wadei ₁₀ , Shelsea A St Hillien ₂ , Danielle Saly ₂ , Nneka N Ufere ₅ , Leigh Anne Dageforde ₁₁ , Kevin R Regner ₁₂ , Justin M Belcher _{13,

14} , Kavish R Patidar _{8,

15} ,

Affiliation

Toronto Centre for Liver Disease, University Health Network, Toronto, Ontario, Canada.
Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Division of Gastroenterology, Department of Medicine, University of California-San Francisco, San Francisco, California, USA.
Baylor University Medical Center, Dallas, Texas, USA.
Liver Center, Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Department of Internal Medicine, University of Michigan Health, Ann Arbor, Michigan, USA.
Division of Gastroenterology and Transplant Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Section of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Department of Transplantation, Mayo Clinic, Jacksonville, Florida, USA.
Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
Division of Nephrology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Section of Nephrology, Department of Internal Medicine, Yale University, New Haven, Connecticut, USA.
CT and VA Connecticut Healthcare, West Haven, Connecticut, USA.
Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas, USA.

The development of acute kidney injury (AKI) in the setting of alcohol-associated hepatitis (AH) portends a poor prognosis. Whether the presence of AH itself drives worse outcomes in patients with cirrhosis and AKI is unknown.

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