A direct chalcone to pyrazole synthetic route to “turn on” and “turn off” fluorescent sensors for Cd²⁺ and Zn²⁺ was developed using CuCl₂ as an in situ oxidant. This one-pot approach produced eight novel pyridine based pyrazole fluorescent sensors displaying both “turn on” and “turn off” properties dependent on the substutient on the aryl ring (4-F, 4-Cl, 4-Br, 4-I, 4-CN, 4-NO₂, 4-OMe and 3,4-OMe). The results within provide valuable insight for future pyrazole sensor design.

中文翻译：

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通过原位芳构化直接从查耳酮一锅法制备吡唑“打开”和“关闭”Zn2+和Cd2+荧光传感器


使用 CuCl ₂ 作为 Cd ²⁺ 和 Zn ²⁺ 的荧光传感器，开发了一种直接查尔酮到吡唑的合成路线，用于“打开”和“关闭”Cd ²⁺ 和 Zn ²⁺ 的荧光传感器。原位氧化剂。这种一锅法产生了八种新型吡啶基吡唑荧光传感器，它们显示出“开启”和“关闭”特性，具体取决于芳环上的取代基（4-F、4-Cl、4-Br、4-I、 4-CN、4-NO ₂ 、4-OMe 和 3,4-OMe)。其中的结果为未来的吡唑传感器设计提供了宝贵的见解。