First described in the 1850s by Wilhelm Krause, the function and physiological functions of the sensory structures that bear his name have remained unclear. However, a study in Nature has shown that Krause corpuscles have an important role in genital sensation.

The team from Harvard University began by assessing the distribution and density of Krause corpuscles. In the genitalia of female mice, corpuscles were densely located throughout the clitoris, but were absent from vaginal tissue. In male mice, corpuscles were distributed through the glans penis and the internal prepuce. Quantitative assessment showed a comparable total number of Krause corpuscles within the glans clitoris and glans penis, despite the different sizes of the female and male genitalia. Thus, the density of Krause corpuscles in the glans clitoris was 15-fold higher than in the flaccid glans penis.

威廉·克劳斯 （Wilhelm Krause） 于 1850 年代首次描述了以他的名字命名的感觉结构的功能和生理功能，至今仍不清楚。然而，《自然》杂志上的一项研究表明，克劳斯小球在生殖器感觉中起着重要作用。

哈佛大学的团队首先评估了克劳斯小球的分布和密度。在雌性小鼠的生殖器中，小细胞密集分布在整个中，但在阴道组织中不存在。在雄性小鼠中，小体通过龟头和包皮内分布。定量评估显示，尽管女性和男性生殖器的大小不同，但龟头阴蒂和龟头内的 Krause 小体总数相当。因此，龟头阴蒂中 Krause 小体的密度比松弛的龟头阴茎高 15 倍。