BackgroundThis study compared titanium and zirconia implant ligature‐induced peri‐implant defect progression and response to regenerative surgical intervention.MethodsEight tissue‐level endosseous implants were placed in 6 mixed‐breed foxhounds, with 2 zirconia and 2 titanium alternating in each hemimandible. Cotton ligatures were placed subgingivally for 16 weeks followed by 8 weeks of spontaneous progression. Standardized radiographs were captured every 2 weeks to evaluate the rate of bone loss. Regenerative surgery was performed utilizing water‐jet decontamination, enamel matrix derivative, and locally harvested autogenous bone. After 16 weeks of healing, final radiographic bone levels as well as probing depths, recession, and clinical attachment levels were assessed.ResultsAll 48 implants integrated successfully. The final average post‐ligature radiographic defects were 2.88 and 3.05 mm for titanium and zirconia implants, respectively. There was no significant difference between materials in the rate of radiographic bone loss (p = 0.09). Following regenerative surgery, the total average amount of radiographic bone gain was 1.41 and 1.20 mm for titanium and zirconia, respectively. The percentage of defect fill was 51.56% and 37.98% (p = 0.03) for titanium and zirconia, respectively. Inter‐group differences were minimal for clinical parameters at the time of sacrifice including periodontal pocket depths (p = 0.81), recession (p = 0.98), or clinical attachment levels (p = 0.51).ConclusionsNo significant difference was found in the rate of peri‐implant defect development between titanium and zirconia implants. Both materials gained significant radiographic bone following regenerative surgery with significantly greater defect percentage fill in titanium implants. The final clinical parameters were similar in both groups.

中文翻译：

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氧化锆与钛种植体周围种植体周围炎的诱发和解决


背景本研究比较了钛和氧化锆种植体结扎引起的种植体周围缺损的进展以及对再生手术干预的反应。方法将八个组织水平骨内种植体放置在 6 只混种猎狐犬中，每只半下颌骨交替放置 2 个氧化锆和 2 个钛。将棉结扎线放置在龈下 16 周，然后进行 8 周的自发进展。每两周拍摄一次标准化放射线照片以评估骨质流失率。再生手术是利用水射流净化、牙釉质基质衍生物和局部采集的自体骨进行的。愈合 16 周后，评估最终的放射线骨水平以及探测深度、后退和临床附着水平。结果所有 48 个种植体均成功整合。钛和氧化锆种植体的最终平均结扎后放射线缺陷分别为 2.88 毫米和 3.05 毫米。不同材料的放射线骨丢失率没有显着差异（ p = 0.09）。再生手术后，钛和氧化锆的放射线骨增量总平均量分别为 1.41 和 1.20 毫米。缺陷填充率分别为51.56%和37.98%（ p = 0.03) 分别适用于钛和氧化锆。处死时的临床参数（包括牙周袋深度）组间差异很小（ p = 0.81），经济衰退（ p = 0.98），或临床依恋水平（ p = 0.51）。结论钛种植体和氧化锆种植体的种植体周围缺损发生率没有显着差异。 这两种材料在再生手术后都获得了显着的射线照相骨，并且钛植入物中的缺陷填充百分比显着提高。两组的最终临床参数相似。