Roxarsone (ROX) is widely used as a feed additive, which is indigestible after ingestion by poultry, and most of it can only be excreted into the natural environment and degraded into highly toxic and carcinogenic inorganic arsenic compounds, which pose a hazard to the ecosystem and human health. However, for roxarsone, traditional detection methods require complex and time-consuming procedures, so it is urgent to find a new fast detection method for detection of ROX. In this work, we developed a novel Raman enhancement material and utilized the Surface-enhanced Raman scattering (SERS) technique to achieve rapid and sensitive detection of roxarsone. Specifically, Mo-doped cobalt layered double hydroxides (Co-LDHs) semiconductor material (abbreviated as CMM-100) was prepared by a simple method of using ion-assisted MOF etching. Under laser excitation at a wavelength of 532 nm, the CMM-100 showed excellent SERS property to various organic dye molecules such as methylene blue (MB), Toluidine Blue(TB), and Crystal Violet (CV). Especially, an enhancement factor (EF) of 1.4 × 10 was achieved for MB. Compared with the traditional method, this work utilized the fast and non-destructive SERS technology, which achieved a rapid detection of ROX. The detection limit was as low as 9.73 × 10 M, and the detection range was from 10 M to 10 M. In this work, SERS technology was adopted for the rapid and sensitive detection of ROX. This study provides a Raman-enhanced substrate named CMMs for detection of food additives, pesticides, biomolecules, etc., which also broadens the application areas of SERS materials.

中文翻译：

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掺钼钴 LDH 作为拉曼增强底物用于检测洛克胂


洛克沙胂（ROX）广泛用作饲料添加剂，家禽摄入后不易消化，大部分只能排泄到自然环境中并降解为剧毒、致癌的无机砷化合物，对生态系统造成危害和人类健康。然而，对于洛克沙胂，传统的检测方法需要复杂且耗时的程序，因此迫切需要寻找一种新的快速检测方法来检测ROX。在这项工作中，我们开发了一种新型拉曼增强材料，并利用表面增强拉曼散射（SERS）技术实现了洛克沙胂的快速、灵敏检测。具体而言，采用离子辅助MOF刻蚀的简单方法制备了Mo掺杂钴层状双氢氧化物（Co-LDHs）半导体材料（简称CMM-100）。在波长 532 nm 的激光激发下，CMM-100 对亚甲基蓝 (MB)、甲苯胺蓝 (TB) 和结晶紫 (CV) 等多种有机染料分子表现出优异的 SERS 性能。特别是，MB 的增强因子 (EF) 达到了 1.4 × 10。与传统方法相比，本工作利用快速、无损的SERS技术，实现了ROX的快速检测。检测限低至9.73×10M，检测范围为10M～10M。本工作采用SERS技术对ROX进行快速、灵敏的检测。本研究为食品添加剂、农药、生物分子等检测提供了拉曼增强基底CMMs，也拓宽了SERS材料的应用领域。