Adverse childhood experiences (ACEs) increase risk for mental illness in women and their children, and dysregulation of the hypothalamic-pituitary-adrenal axis may play a role. The impact of ACEs on the hypothalamic-pituitary-adrenal axis may be strongest when ACEs occur prepubertally and in people who are exposed to abuse ACEs.

中文翻译：

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暴露于童年逆境的母亲的婴儿压力诱导的皮质醇反应的性别差异


童年期不良经历 （ACE） 会增加女性及其儿童患精神疾病的风险，下丘脑-垂体-肾上腺轴的失调可能起作用。当 ACE 发生在青春期前和暴露于滥用 ACE 的人群中时，ACEs 对下丘脑-垂体-肾上腺轴的影响可能最强。