Extract

Randomised controlled trials (RCTs) are regarded as the gold standard for assessing the efficacy and safety of treatments, and thus for guiding medical decisions. Although they are an essential element in clinical research, they do not always reflect the reality of clinical practice. Indeed, because of their rigorous methodology, their strict selection criteria and the fact that patients are monitored in a highly controlled environment, RCTs have a high degree of internal validity, but their transferability to real life is sometimes questionable.

中文翻译：

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哮喘的真实世界证据：除了随机对照试验之外，还能期待什么？

 提炼

随机对照试验（RCT）被视为评估治疗效果和安全性的黄金标准，从而指导医疗决策。尽管它们是临床研究的重要组成部分，但它们并不总是反映临床实践的现实。事实上，由于其严格的方法论、严格的选择标准以及在高度控制的环境中对患者进行监测的事实，随机对照试验具有高度的内部有效性，但它们向现实生活的转移有时是值得怀疑的。