Fluorescence guidance is utilized to increase the chances of complete tumour resection while balancing preservation of neurological function in glioma surgery. A multimodal optical microscope capable of imaging the histology and fluorescence of fresh human brain specimens revealed an unexpected pattern of fluorophore accumulation and a new means of visualizing macrophages during surgery.

中文翻译：

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光学显微镜和转录组学揭示神经胶质瘤手术中荧光的起源


在神经胶质瘤手术中，利用荧光引导来增加肿瘤完全切除的机会，同时平衡神经功能的保留。能够对新鲜人脑标本的组织学和荧光进行成像的多模态光学显微镜揭示了荧光团积累的意想不到的模式以及手术期间可视化巨噬细胞的新方法。