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Microbiota alert: Proteobacteria consume arginine to dampen omental antitumor immunity
Cell Host & Microbe ( IF 20.6 ) Pub Date : 2024-07-10 , DOI: 10.1016/j.chom.2024.05.020 Xian Du 1 , Zuliang Jie 2 , Qiang Zou 1
中文翻译:
微生物群警报:变形菌消耗精氨酸来抑制大网膜抗肿瘤免疫力
更新日期:2024-07-10
Cell Host & Microbe ( IF 20.6 ) Pub Date : 2024-07-10 , DOI: 10.1016/j.chom.2024.05.020 Xian Du 1 , Zuliang Jie 2 , Qiang Zou 1
Affiliation
The microbiota can impact antitumor immunity, but whether the microbiota regulates omental antitumor immunity remains elusive. In this issue of Cell Host & Microbe, Meza-Perez et al. demonstrated that Proteobacteria consume arginine to increase Treg cell suppressive capacity and inhibit antitumor immune responses, promoting tumor growth in the omentum.
中文翻译:
微生物群警报:变形菌消耗精氨酸来抑制大网膜抗肿瘤免疫力
微生物群可以影响抗肿瘤免疫,但微生物群是否调节大网膜抗肿瘤免疫仍不清楚。在本期《细胞宿主与微生物》中,Meza-Perez 等人。证明变形菌消耗精氨酸来增加 Treg 细胞抑制能力并抑制抗肿瘤免疫反应,促进大网膜肿瘤生长。