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Correction to “Structure–Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials”
Journal of Medicinal Chemistry ( IF 6.8 ) Pub Date : 2024-07-10 , DOI: 10.1021/acs.jmedchem.4c01411 John A. Gilleran , Kutub Ashraf , Melvin Delvillar , Tyler Eck , Raheel Fondekar , Edward B. Miller , Ashley Hutchinson , Aiping Dong , Alma Seitova , Mariana Laureano De Souza , David Augeri , Levon Halabelian , John Siekierka , David P. Rotella , John Gordon , Wayne E. Childers , Mark C. Grier , Bart L. Staker , Jacques Y. Roberge , Purnima Bhanot
Journal of Medicinal Chemistry ( IF 6.8 ) Pub Date : 2024-07-10 , DOI: 10.1021/acs.jmedchem.4c01411 John A. Gilleran , Kutub Ashraf , Melvin Delvillar , Tyler Eck , Raheel Fondekar , Edward B. Miller , Ashley Hutchinson , Aiping Dong , Alma Seitova , Mariana Laureano De Souza , David Augeri , Levon Halabelian , John Siekierka , David P. Rotella , John Gordon , Wayne E. Childers , Mark C. Grier , Bart L. Staker , Jacques Y. Roberge , Purnima Bhanot
Page 3474. In the subsection of the Results with the heading R3–In VitroSAR Trend, the sentence “However, our analysis of the 3-methylpiperidine analogs 40–41 (cis and trans racemates), noted a marked improvement in potency, particularly in the EC50 measurements in cellular assays.” should read “However, our analysis of the 3-methylpiperidine analogs 38–39 (cis and trans racemates) noted a marked improvement in potency, particularly in the EC50 measurements in cellular assays.” This article has not yet been cited by other publications.
中文翻译:
对“基于吡咯的系列 PfPKG 抑制剂作为抗疟疾药物的结构-活性关系”的更正
第 3474 页。在结果的小节中,标题为R 3 –体外SAR 趋势,句子“然而,我们对 3-甲基哌啶类似物40 – 41 (顺式和反式外消旋体)的分析表明效力显着提高,特别是在细胞检测中的 EC 50测量中。”应阅读“然而,我们对 3-甲基哌啶类似物38 – 39 (顺式和反式外消旋体)的分析表明效力显着提高,特别是在细胞测定中的 EC 50测量中。”这篇文章尚未被其他出版物引用。
更新日期:2024-07-10
中文翻译:
对“基于吡咯的系列 PfPKG 抑制剂作为抗疟疾药物的结构-活性关系”的更正
第 3474 页。在结果的小节中,标题为R 3 –体外SAR 趋势,句子“然而,我们对 3-甲基哌啶类似物40 – 41 (顺式和反式外消旋体)的分析表明效力显着提高,特别是在细胞检测中的 EC 50测量中。”应阅读“然而,我们对 3-甲基哌啶类似物38 – 39 (顺式和反式外消旋体)的分析表明效力显着提高,特别是在细胞测定中的 EC 50测量中。”这篇文章尚未被其他出版物引用。