Inverse association between (poly)phenol intake and age-related disorders has been demonstrated; however, little is known whether they affect comprehensively assessed healthy aging. The aim of this study was to evaluate the associations between the intake of (poly)phenol (including selected classes and subclasses) and healthy aging scores related to biopsychosocial aspects of health and functioning. A cross-sectional study was performed using data on 9774 randomly selected citizens of Krakow (Poland) who were 45–69 years of age. Dietary (poly)phenol intake was evaluated using a food frequency questionnaire and matching food consumption data with the Phenol-Explorer database. The healthy aging scores were estimated from the ATHLOS Healthy Ageing Scale (HAS) developed by the Ageing Trajectories of Health-Longitudinal Opportunities and Synergies (ATHLOS) consortium. Beta coefficients were calculated using multivariable linear regression models. In multivariable adjusted models, there were significant positive associations between the ATHLOS HAS score and intake of total (poly)phenols (b per increase of 100 mg/day = 0.081; 95% CI, 0.050; 0.112) and among main classes of (poly)phenols with phenolic acids (b = 0.139; 95% CI, 0.098; 0.180). Intake of remaining classes of (poly)phenols (flavonoids, lignans, stilbenes, and others) was not related to the ATHLOS HAS score. Among individual classes studied, hydroxycinnamic acids, flavonols, flavones, and dihydrochalcones were associated with better healthy aging. The findings suggest the beneficial effect of total dietary (poly)phenol and some classes and subclasses of (poly)phenol intake in terms of healthy aging in Poland. These findings should be confirmed in other settings and with prospective data.

已证明（多）苯酚摄入量与年龄相关疾病之间呈负相关；然而，很少有人知道它们是否会影响综合评估的健康老龄化。本研究的目的是评估（多）苯酚（包括选定的类别和亚类）的摄入量与与健康和功能的生物心理社会方面相关的健康老龄化评分之间的关​​联。使用随机选择的 9774 名克拉科夫（波兰）45-69 岁公民的数据进行了一项横断面研究。使用食物频率调查问卷并将食物消耗数据与 Phenol-Explorer 数据库相匹配来评估膳食（多）苯酚摄入量。健康老龄化得分是根据健康老龄化轨迹-纵向机会和协同（ATHLOS）联盟开发的ATHLOS健康老龄化量表（HAS）估算的。使用多元线性回归模型计算 Beta 系数。在多变量调整模型中，ATHLOS HAS 评分与总（多）酚摄入量之间存在显着正相关（ b每增加 100 毫克/天 = 0.081；95% CI，0.050；0.112），并且在主要类别（多）之间存在显着正相关。 ) 苯酚与酚酸 ( b = 0.139; 95% CI, 0.098; 0.180)。其余类别的（多）酚（类黄酮、木酚素、芪等）的摄入量与 ATHLOS HAS 评分无关。在研究的各个类别中，羟基肉桂酸、黄酮醇、黄酮和二氢查尔酮与更好的健康衰老相关。研究结果表明，总膳食（多）苯酚以及（多）苯酚的某些类别和亚类摄入量对波兰的健康老龄化具有有益影响。这些发现应该在其他环境和前瞻性数据中得到证实。