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Itaconate targets fibroblast-like synoviocytes in RA
Nature Reviews Rheumatology ( IF 29.4 ) Pub Date : 2024-07-10 , DOI: 10.1038/s41584-024-01142-4
Sarah Onuora 1
Affiliation  

Treatment with the endogenous metabolite itaconate induced phenotypic and metabolic changes in fibroblast-like synoviocytes and reduced the severity of arthritis in an animal model.

中文翻译:


衣康酸靶向 RA 中的成纤维细胞样滑膜细胞



在动物模型中,用内源性代谢物衣康酸治疗可诱导成纤维样滑膜细胞的表型和代谢变化,并减轻关节炎的严重程度。
更新日期:2024-07-10
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