Post-burn endocrine–immune dynamics and ageing considerations,Nature Reviews Endocrinology

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Post-burn endocrine–immune dynamics and ageing considerations
Nature Reviews Endocrinology ( IF 31.0 ) Pub Date : 2024-07-09 , DOI: 10.1038/s41574-024-01018-3
Fadi Khalaf _{1,

2,

3} , Zachary Ricciuti _{2,

3,

4} , Dalia Barayan _{2,

3,

5} , Stephanie Wojtowicz-Piotrowski _{2,

3,

5} , Marc G Jeschke _{1,

2,

3,

4,

5}

Affiliation

Thermal injuries trigger stress-induced endocrine responses that are critical for survival. With age, these responses falter, which results in an inability to combat burn-induced dysfunction and greatly increased mortality. Current knowledge about the post-burn endocrine response in older adults is sparse, which leaves therapeutic gaps for this vulnerable and expanding demographic.

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