People with diabetes mellitus (DM) have an increased probability of progressing to Alzheimer disease (AD) in the first year after a diagnosis of mild cognitive impairment (MCI), a study based on data from the AD Neuroimaging Initiative has shown. Propensity score matching was performed in 306 people with MCI, 102 of whom also had DM. By the end of the 12-month follow-up period, 8.82% of the DM group and 2.45% of the non-DM group had developed AD. The results suggest that people with DM could benefit from early therapeutic intervention — to improve glycaemic control, for example — following an MCI diagnosis.

中文翻译：

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糖尿病可能加速 MCI 向 AD 的转化

一项基于 AD 神经影像计划数据的研究显示，糖尿病 (DM) 患者在诊断出轻度认知障碍 (MCI) 后的第一年，进展为阿尔茨海默病 (AD) 的可能性增加。对 306 名 MCI 患者进行了倾向评分匹配，其中 102 名患者还患有 DM。到12个月的随访期结束时，8.82%的DM组和2.45%的非DM组出现了AD。结果表明，糖尿病患者在 MCI 诊断后可以从早期治疗干预中受益，例如改善血糖控制。