This review provides a comprehensive overview of the advancements and potential applications of calcium peroxide nanoparticles (CaO NPs) in combating bacterial infections. With the rise of antibiotic resistance posing a significant global health threat, alternative antibacterial agents like CaO NPs have garnered increasing attention. The review begins by discussing the synthesis and functionalization of CaO NPs, highlighting recent developments in nanoparticle engineering techniques. Subsequently, it explores the intricate antibacterial mechanisms of CaO NPs, emphasizing their ability to generate reactive oxygen species and disrupt bacterial biofilms. Evaluation of CaO NPs' antibacterial efficacy against a broad spectrum of pathogens, coupled with discussions on potential applications in various fields including biomedical and environmental remediation, underscores their promising role as effective antibacterial agents. The review also addresses challenges such as nanoparticle stability and biocompatibility, and proposes future research directions to fully exploit the therapeutic potential of CaO NPs. Overall, this review consolidates current knowledge on CaO NPs and advocates for their continued exploration in combating bacterial infections.

中文翻译：

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纳米过氧化钙抗菌活性的研究进展与展望


本综述全面概述了过氧化钙纳米粒子（CaO NP）在对抗细菌感染方面的进展和潜在应用。随着抗生素耐药性的增加对全球健康构成重大威胁，CaO NPs 等替代抗菌剂引起了越来越多的关注。该综述首先讨论了 CaO 纳米颗粒的合成和功能化，重点介绍了纳米颗粒工程技术的最新发展。随后，它探索了 CaO NP 的复杂抗菌机制，强调它们产生活性氧和破坏细菌生物膜的能力。对 CaO NPs 对多种病原体的抗菌功效的评估，加上对生物医学和环境修复等各个领域的潜在应用的讨论，强调了它们作为有效抗菌剂的前景。该综述还解决了纳米颗粒稳定性和生物相容性等挑战，并提出了充分利用 CaO 纳米颗粒的治疗潜力的未来研究方向。总的来说，这篇综述巩固了目前关于 CaO NP 的知识，并提倡继续探索它们在对抗细菌感染方面的作用。