The antibacterial activity of reduced graphene oxide fibers (rGOFs) fabricated by a one-step dimensionally confined hydrothermal technique was investigated on both Gram-positive and Gram-negative models of bacteria in this study. The surface morphology, microstructure, and chemical composition of the as-prepared rGOFs were determined using scanning electron microscopy (SEM), X-ray diffraction, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy (XPS), and Raman spectroscopy. SEM images showed the fiber to have an average diameter of 46.6 ± 0.53 μm, composed of rGO nanosheets with numerous sharp edges. XPS and Raman spectroscopy confirmed the presence of -bonded carbon and structural defects in the samples. Antibacterial properties of rGOFs were tested and analyzed using agar well diffusion, colony counting method, SEM observation, and reactive oxygen species generation. The excellent broad-spectrum antibacterial ability of rGOFs is attributed to the physicochemical properties and unique surface morphological features of the samples, which could facilitate the development of rGOFs-based biomaterial for various biomedical and nano-technological applications such as a promising antibacterial agent or an implant/scaffold for nerve tissue engineering and regeneration.

中文翻译：

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水热法制备还原氧化石墨烯纤维的抗菌性能


本研究在革兰氏阳性和革兰氏阴性细菌模型上研究了通过一步维限制水热技术制备的还原氧化石墨烯纤维（rGOF）的抗菌活性。使用扫描电子显微镜（SEM）、X射线衍射、傅里叶变换红外光谱、X射线光电子能谱（XPS）和拉曼光谱测定了所制备的rGOF的表面形貌、微观结构和化学成分。 SEM 图像显示该纤维的平均直径为 46.6 ± 0.53 μm，由具有许多锋利边缘的 rGO 纳米片组成。 XPS 和拉曼光谱证实了样品中存在键合碳和结构缺陷。采用琼脂孔扩散法、菌落计数法、SEM观察、活性氧产生等方法对rGOFs的抗菌性能进行了测试和分析。 rGOFs优异的广谱抗菌能力归因于样品的理化性质和独特的表面形态特征，这可以促进基于rGOFs的生物材料的开发，用于各种生物医学和纳米技术应用，例如有前途的抗菌剂或用于神经组织工程和再生的植入物/支架。