Alterations in vestibular sensory processing following G-transitions lead to head movement sensitivity and motion sickness upon return to Earth's gravity. The purpose of this study was to evaluate whether a non-pharmaceutical tool using dual, opposing-phase galvanic vestibular stimulation (oGVS) could suppress disorienting illusions and mitigate motion sickness. Using a repeated measures counter-balanced design, motion sickness and perception were obtained in 27 subjects during Coriolis cross-coupling stimuli on a rotating chair across three oGVS interventions: throughout stimulus testing (prevention), following symptom onset (rescue), and without stimulation (control). The oGVS peak current was ±2.25 mA during prevention and rescue sessions. During pitch head movements, subjects were asked to use a joystick to record the magnitude of their perceived rotation along three axes. The motion sickness symptom scoring was obtained using the Pensacola Diagnostic Index and Subjective Discomfort Rating. Performance on a sensorimotor and cognitive test battery was measured during an initial session to map changes in oGVS level with functional performance. The symptom onset was delayed during the Prevention session. Initiating oGVS following symptom onset did not appear to alter the symptom progression. Based on the joystick measures, oGVS reduced the perceived roll and pitch sensation during head movements. The comparable levels of oGVS did not impair performance on the functional test battery including mobility, balance and oculometric tasks. Our findings suggest oGVS may be useful in reducing disorienting roll and pitch illusions and delaying the onset of motion sickness.

中文翻译：

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双反相电流前庭刺激可改变科里奥利交叉耦合的感知并延迟晕动病的发作


G 转变后前庭感觉处理的改变会导致头部运动敏感，并在返回地球重力时出现晕动病。本研究的目的是评估使用双反相电流前庭刺激 (oGVS) 的非药物工具是否可以抑制迷失方向的错觉并减轻晕动病。使用重复测量平衡设计，在旋转椅上进行科里奥利交叉耦合刺激期间，通过三种 oGVS 干预措施，在 27 名受试者中获得了晕动病和知觉：整个刺激测试（预防）、症状出现后（救援）和无刺激（控制）。在预防和救援过程中，oGVS 峰值电流为 ±2.25 mA。在俯仰头部运动期间，受试者被要求使用操纵杆记录他们感知到的沿三个轴旋转的幅度。使用彭萨科拉诊断指数和主观不适评级获得晕动病症状评分。在初始会话期间测量感觉运动和认知测试电池的表现，以将 oGVS 水平的变化与功能表现对应起来。在预防会议期间，症状的出现被推迟。症状出现后开始 oGVS 似乎并没有改变症状的进展。基于操纵杆测量，oGVS 减少了头部运动期间感知的滚动和俯仰感觉。类似水平的 oGVS 不会影响功能测试电池的性能，包括移动性、平衡性和眼测量任务。我们的研究结果表明，oGVS 可能有助于减少令人迷失方向的滚动和俯仰错觉并延缓晕动病的发生。