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Monkey see, monkey do: Tracking iPS-cardiomyocyte survival and maturation in autografts
Cell Stem Cell ( IF 19.8 ) Pub Date : 2024-07-05 , DOI: 10.1016/j.stem.2024.06.006
Xiaoqian Ji 1 , Qiyuan Wang 2 , Nan Cao 3
Affiliation  

Induced pluripotent stem cell-derived cardiomyocyte (iPSC-CM) therapy has emerged as a highly promising field of heart repair. Lin et al.1 presented compelling evidence on the long-term engraftment and maturation of autologous iPSC-CMs in two rhesus macaques, demonstrating unprecedented cardiac autografting data in large animal models without the need of immunosuppressants.



中文翻译:


猴看猴做:追踪自体移植物中 iPS 心肌细胞的存活和成熟



诱导多能干细胞源性心肌细胞(iPSC-CM)疗法已成为心脏修复领域极具前景的领域。林等人。 1提供了关于自体 iPSC-CM 在两只恒河猴中长期植入和成熟的令人信服的证据,展示了在大型动物模型中无需免疫抑制剂的前所未有的自体心脏移植数据。

更新日期:2024-07-05
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