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Unraveling the function of FGF signaling in human hypoblast specialization
Cell Stem Cell ( IF 19.8 ) Pub Date : 2024-07-05 , DOI: 10.1016/j.stem.2024.06.010 Hao Wu 1 , Jinglei Zhai 1 , Hongmei Wang 1
中文翻译:
揭示 FGF 信号在人类下胚层特化中的功能
更新日期:2024-07-05
Cell Stem Cell ( IF 19.8 ) Pub Date : 2024-07-05 , DOI: 10.1016/j.stem.2024.06.010 Hao Wu 1 , Jinglei Zhai 1 , Hongmei Wang 1
Affiliation
Dattani et al.1 developed a method for inducing hypoblast-like cells from human naive pluripotent stem cells. They elucidated the requirement for FGF signaling in human hypoblast specialization at a specific time window, which was previously controversial.
中文翻译:
揭示 FGF 信号在人类下胚层特化中的功能
达塔尼等人。 1开发了一种从人类幼稚多能干细胞诱导下胚层样细胞的方法。他们阐明了人类下胚层特化在特定时间窗口对 FGF 信号传导的需求,这在之前是有争议的。