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ASS1: Guardian of the genome
Nature Reviews Cancer ( IF 72.5 ) Pub Date : 2024-07-05 , DOI: 10.1038/s41568-024-00724-4
Gabrielle Brewer 1
Affiliation  

Lim et al. show that ASS1, silenced in many cancer types, is a metabolic checkpoint that, following DNA damage, halts cell cycle progression by restricting nucleotide synthesis and p53-related gene transcription.

中文翻译:


ASS1:基因组的守护者



林等人。研究表明,在许多癌症类型中沉默的 ASS1 是一个代谢检查点,在 DNA 损伤后,它通过限制核苷酸合成和 p53 相关基因转录来停止细胞周期进程。
更新日期:2024-07-05
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