Cachexia, a syndrome with high prevalence in non-small cell lung cancer patients, impairs quality of life and reduces tolerance and responsiveness to cancer therapy resulting in decreased survival. Optimal nutritional care is pivotal in the treatment of cachexia and a recommended cornerstone of multimodal therapy. Here, we investigated the therapeutic effect of an intervention diet consisting of a specific combination of high protein, leucine, fish oil, vitamin D, galacto-oligosaccharides, and fructo-oligosaccharides on the development and progression of cachexia in an orthotopic lung cancer mouse model.

中文翻译：

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有针对性的营养干预减轻实验性肺癌恶病质


恶病质是一种在非小细胞肺癌患者中发病率较高的综合征，它会损害生活质量，降低对癌症治疗的耐受性和反应性，导致生存率下降。最佳营养护理对于恶病质的治疗至关重要，也是多模式治疗的推荐基石。在这里，我们研究了由高蛋白、亮氨酸、鱼油、维生素 D、低聚半乳糖和低聚果糖的特定组合组成的干预饮食对原位肺癌小鼠模型恶病质发生和进展的治疗效果。