ObjectiveDetermine prevalence, risk factors and outcomes of hypertensive disorders in pregnancy (HDP).DesignCross‐sectional analysis of data captured in the Maternal and Perinatal Database for Quality, Equity and Dignity (MPD‐4‐QED) between September 2019 and August 2020.SettingFifty‐four referral level facilities in Nigeria.PopulationWomen whose pregnancy ended (irrespective of the location or duration of pregnancy) or who were admitted within 42 days of delivery.MethodsDescriptive statistics and multilevel mixed‐effects logistic regression models.Main Outcome MeasuresPrevalence of HDP, sociodemographic and clinical factors associated with HDP and perinatal outcomes.ResultsAmong the 71 758 women 6.4% had HDP and gestational hypertension accounted for 49.8%. Preeclampsia and eclampsia were observed in 9.5% and 7.0% of all pregnancies, respectively. The predictors of HDP were age over 35 years (OR1.96, 95% CI 1.82–2.12; p < 0.001), lack of formal educational (OR 1.18, 95% CI 1.06–1.32; p = 0.002), primary level of education (OR 1.20, 95% CI 1.03–1.4; p < 0.002), nulliparity (OR 1.21, 95% CI 1.12–1.31; p < 0.001), grand‐multiparity (OR 1.36, 95%CI 1.21–1.52; p < 0.001), previous caesarean section (OR 1.26, 95%CI 1.15–1.38; p < 0.001) and previous miscarriage (OR 1.22, 95% CI 1.13–1.31; p < 0.001). Overall 3.7% of the patients with HDP died, with eclampsia having the highest case fatality rate of 27.9%. Stillbirth occurred in 11.9% of pregnancies with hypertensive disorders.ConclusionsHypertensive disorders in pregnancy are not uncommon in Nigeria. They are associated with adverse outcomes with over one‐quarter of women with eclampsia dying. The main predictors include older age, poor education, extremes of parity and previous CS or miscarriage. Maternal and perinatal outcomes are poor with about a quarter developing complications and about 1 in 10 having stillbirths.

中文翻译：

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尼日利亚三级卫生机构妊娠期高血压疾病的预测因素、患病率和结果：对孕产妇和围产期质量、公平和尊严计划数据库的二次分析


目的确定妊娠期高血压疾病 (HDP) 的患病率、危险因素和结果。设计对 2019 年 9 月至 2020 年 8 月期间孕产妇和围产期质量、公平和尊严数据库 (MPD-4-QED) 中捕获的数据进行横断面分析。SettingFifty ‐尼日利亚的四个转诊级设施。人口妊娠结束（无论妊娠地点或持续时间）或在分娩 42 天内入院的妇女。方法描述性统计和多级混合效应逻辑回归模型。主要结果指标 HDP 的患病率、社会人口统计学结果71 758名妇女中，6.4%患有HDP，妊娠期高血压占49.8%。在所有妊娠中，先兆子痫和子痫的发生率分别为 9.5% 和 7.0%。 HDP 的预测因素是年龄超过 35 岁（OR1.96，95% CI 1.82–2.12； p < 0.001），缺乏正规教育（OR 1.18，95% CI 1.06–1.32； p = 0.002），小学教育水平（OR 1.20，95% CI 1.03–1.4； p < 0.002），未产（OR 1.21，95% CI 1.12–1.31； p < 0.001), 巨多产 (OR 1.36, 95%CI 1.21–1.52; p < 0.001），既往剖腹产（OR 1.26，95%CI 1.15–1.38； p < 0.001）和既往流产史（OR 1.22，95% CI 1.13–1.31； p < 0.001）。 HDP患者总体死亡率为3.7%，其中子痫病死率最高，为27.9%。患有高血压疾病的孕妇中有 11.9% 发生死产。结论 妊娠期高血压疾病在尼日利亚并不罕见。它们与超过四分之一的子痫女性死亡的不良后果相关。 主要预测因素包括年龄较大、教育程度低、胎次极端以及既往有过流产史或流产史。孕产妇和围产期结局很差，大约四分之一出现并发症，大约十分之一出现死产。