In Vitro Protective Effect of Pea-Derived Peptides (PPs) via the Keap1/Nrf2 Signaling Pathway on Alpha-Gliadin-Sensitizing Peptide Induced Cacao-2 Cells,Molecular Nutrition & Food Research

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In Vitro Protective Effect of Pea-Derived Peptides (PPs) via the Keap1/Nrf2 Signaling Pathway on Alpha-Gliadin-Sensitizing Peptide Induced Cacao-2 Cells
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2024-07-03 , DOI: 10.1002/mnfr.202400010
Bing Gao ₁ , Chenxu Cui ₂ , Fang Yan ₁ , Ning Li ₃ , Xuefeng Sun ₂ , Fangyu Wang ₂ , Chunfeng Wang ₁

Affiliation

Celiac disease (CD) is an allergic intestinal disease caused mainly by gliadin in wheat, which is widespread in the population and currently lacks effective treatment. α-Gliadin peptides cause cellular damage by substantially increasing cellular reactive oxygen species (ROS) levels.

中文翻译：

豌豆源肽 (PP) 通过 Keap1/Nrf2 信号通路对 α-麦醇溶蛋白敏化肽诱导的 Cacao-2 细胞的体外保护作用

乳糜泻（CD）是一种主要由小麦中的麦醇溶蛋白引起的过敏性肠道疾病，在人群中广泛存在，目前缺乏有效的治疗方法。 α-麦醇溶蛋白肽通过大幅增加细胞活性氧 (ROS) 水平来引起细胞损伤。

更新日期：2024-07-03

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