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Extended genome-wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry
Alzheimer's & Dementia ( IF 13.0 ) Pub Date : 2024-07-03 , DOI: 10.1002/alz.13880 Nicholas R Ray 1 , Brian W Kunkle 2 , Kara Hamilton-Nelson 2 , Jiji T Kurup 1 , Farid Rajabli 2 , Min Qiao 1 , Badri N Vardarajan 1 , Mehmet I Cosacak 3 , Caghan Kizil 1 , Melissa Jean-Francois 2 , Michael Cuccaro 2 , Dolly Reyes-Dumeyer 1 , Laura Cantwell 4 , Amanda Kuzma 4 , Jeffery M Vance 2 , Sujuan Gao 5 , Hugh C Hendrie 6 , Olusegun Baiyewu 7 , Adesola Ogunniyi 7 , Rufus O Akinyemi 7 , , Wan-Ping Lee 4 , Eden R Martin 2, 8 , Li-San Wang 4 , Gary W Beecham 2 , William S Bush 9, 10 , Wanying Xu 9 , Fulai Jin 9, 10 , Liyong Wang 2 , Lindsay A Farrer 11, 12, 13, 14, 15 , Jonathan L Haines 10 , Goldie S Byrd 16 , Gerard D Schellenberg 4 , Richard Mayeux 1, 17, 18, 19, 20 , Margaret A Pericak-Vance 2, 8 , Christiane Reitz 1, 17, 18, 20
Alzheimer's & Dementia ( IF 13.0 ) Pub Date : 2024-07-03 , DOI: 10.1002/alz.13880 Nicholas R Ray 1 , Brian W Kunkle 2 , Kara Hamilton-Nelson 2 , Jiji T Kurup 1 , Farid Rajabli 2 , Min Qiao 1 , Badri N Vardarajan 1 , Mehmet I Cosacak 3 , Caghan Kizil 1 , Melissa Jean-Francois 2 , Michael Cuccaro 2 , Dolly Reyes-Dumeyer 1 , Laura Cantwell 4 , Amanda Kuzma 4 , Jeffery M Vance 2 , Sujuan Gao 5 , Hugh C Hendrie 6 , Olusegun Baiyewu 7 , Adesola Ogunniyi 7 , Rufus O Akinyemi 7 , , Wan-Ping Lee 4 , Eden R Martin 2, 8 , Li-San Wang 4 , Gary W Beecham 2 , William S Bush 9, 10 , Wanying Xu 9 , Fulai Jin 9, 10 , Liyong Wang 2 , Lindsay A Farrer 11, 12, 13, 14, 15 , Jonathan L Haines 10 , Goldie S Byrd 16 , Gerard D Schellenberg 4 , Richard Mayeux 1, 17, 18, 19, 20 , Margaret A Pericak-Vance 2, 8 , Christiane Reitz 1, 17, 18, 20
Affiliation
Despite a two-fold risk, individuals of African ancestry have been underrepresented in Alzheimer's disease (AD) genomics efforts.
中文翻译:
利用非洲基因组资源小组进行的扩展全基因组关联研究确定了非洲血统个体中阿尔茨海默病的新易感位点
尽管存在两倍的风险,非洲血统的个体在阿尔茨海默病(AD)基因组学研究中的代表性仍然不足。
更新日期:2024-07-03
中文翻译:
![](https://scdn.x-mol.com/jcss/images/paperTranslation.png)
利用非洲基因组资源小组进行的扩展全基因组关联研究确定了非洲血统个体中阿尔茨海默病的新易感位点
尽管存在两倍的风险,非洲血统的个体在阿尔茨海默病(AD)基因组学研究中的代表性仍然不足。