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Modelling the innate immune system in microphysiological systems
Lab on a Chip ( IF 6.1 ) Pub Date : 2024-07-03 , DOI: 10.1039/d3lc00812f
Michael J. Rupar 1 , Hannah Hanson 1 , Stephanie Rogers 1 , Brianna Botlick 1 , Steven Trimmer 1 , James J. Hickman 1
Affiliation  

This critical review aims to highlight how modeling of the immune response has adapted over time to utilize microphysiological systems. Topics covered here will discuss the integral components of the immune system in various human body systems, and how these interactions are modeled using these systems. Through the use of microphysiological systems, we have not only expanded on foundations of basic immune cell information, but have also gleaned insight on how immune cells work both independently and collaboratively within an entire human body system.

中文翻译:


在微生理系统中模拟先天免疫系统



这篇批判性评论旨在强调免疫反应模型如何随着时间的推移而适应利用微生理系统。这里讨论的主题将讨论各种人体系统中免疫系统的组成部分,以及如何使用这些系统对这些相互作用进行建模。通过使用微生理系统,我们不仅扩展了基本免疫细胞信息的基础,而且还深入了解了免疫细胞如何在整个人体系统中独立和协作地工作。
更新日期:2024-07-03
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