The unique ability of piezoelectric materials to generate electricity spontaneously has attracted widespread interest in the medical field. In addition to the ability to convert mechanical stress into electrical energy, piezoelectric materials offer the advantages of high sensitivity, stability, accuracy and low power consumption. Because of these characteristics, they are widely applied in devices such as sensors, controllers and actuators. However, piezoelectric materials also show great potential for the medical manufacturing of artificial organs and for tissue regeneration and repair applications. For example, the use of piezoelectric materials in cochlear implants, cardiac pacemakers and other equipment may help to restore body function. Moreover, recent studies have shown that electrical signals play key roles in promoting tissue regeneration. In this context, the application of electrical signals generated by piezoelectric materials in processes such as bone healing, nerve regeneration and skin repair has become a prospective strategy. By mimicking the natural bioelectrical environment, piezoelectric materials can stimulate cell proliferation, differentiation and connection, thereby accelerating the process of self-repair in the body. However, many challenges remain to be overcome before these concepts can be applied in clinical practice, including material selection, biocompatibility and equipment design. On the basis of the principle of electrical signal regulation, this article reviews the definition, mechanism of action, classification, preparation and current biomedical applications of piezoelectric materials and discusses opportunities and challenges for their future clinical translation.

中文翻译：

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从电力到活力：压电材料在组织再生中的新兴应用


压电材料具有独特的自发发电能力，引起了医疗领域的广泛兴趣。除了能够将机械应力转化为电能外，压电材料还具有高灵敏度、稳定性、精度和低功耗等优点。由于这些特性，它们被广泛应用于传感器、控制器和执行器等设备中。然而，压电材料在人工器官的医疗制造和组织再生和修复应用中也显示出巨大的潜力。例如，在人工耳蜗、心脏起搏器和其他设备中使用压电材料可能有助于恢复身体功能。此外，最近的研究表明，电信号在促进组织再生中起着关键作用。在此背景下，将压电材料产生的电信号应用于骨愈合、神经再生和皮肤修复等过程已成为一种前瞻性策略。压电材料通过模仿自然生物电环境，可以刺激细胞增殖、分化和连接，从而加速体内的自我修复过程。然而，在将这些概念应用于临床实践之前，仍有许多挑战需要克服，包括材料选择、生物相容性和设备设计。本文基于电信号调控原理，综述了压电材料的定义、作用机理、分类、制备和当前生物医学应用，并探讨了其未来临床转化的机遇和挑战。