Efforts to integrate computational tools for variant effect prediction into the process of clinical decision-making are in progress. However, for such efforts to succeed and help to provide more informed clinical decisions, it is necessary to enhance transparency and address the current limitations of computational predictors.

中文翻译：

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提高变异效应预测计算工具的透明度


将变异效应预测的计算工具整合到临床决策过程中的努力正在进行中。然而，为了使此类努力取得成功并帮助提供更明智的临床决策，有必要提高透明度并解决计算预测变量当前的局限性。