Chitosan (CS), a versatile biopolymer known for its diverse bioactivity, is commonly used as a coating or finishing agent to enhance fabric performance and broaden their applications. However, conventional methods for introducing CS coating layer on the fabrics often relies on using composition to control their functionality, limiting the ability to tailor properties for specific needs. In this study, we introduce an innovative coating platform utilizing drying, ionic gelation, or a combination of both to control the morphology and amino-protonation degree of CS. This approach allows the development of three distinct functional CS coatings from the same material composition. The method is effectively applied to cotton and polylactic acid (PLA)-based non-woven fabrics, preserving the permeability, breathability, and mechanical properties of the substrates. By varying processing conditions, it is found that CS coatings can impart distinct functions to the fabrics upon their morphology, such as attaining high degree of hydrophobicity (with a water contact angle reaching 129°), broad-spectrum antibacterial activity (>99.99 %) for the sample prepared by combined drying and ionic gelation methods. Additionally, our CS-coated fabrics can exhibit good biocompatibility, as demonstrated by cytocompatibility and histocompatibility evaluations, while excellent anti-adhesive properties and healing performance in infected wound models in rats can be obtained with the presence of CS microsphere. Our methods are straightforward and potentially scalable, enabling modular control over the functionality of CS-coated fabrics to meet diverse requirements. This work offers a promising strategy for modifying fabric properties with CS coatings, making it suitable for various applications such as facial masks, dressings, and antibacterial textiles.

中文翻译：

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调节壳聚糖涂层的形态和质子化程度以实现受控的织物功能化


壳聚糖 (CS) 是一种多功能生物聚合物，以其多种生物活性而闻名，通常用作涂层或整理剂，以增强织物性能并拓宽其应用。然而，在织物上引入 CS 涂层的传统方法通常依赖于使用成分来控制其功能，从而限制了根据特定需求定制性能的能力。在这项研究中，我们引入了一种创新的涂层平台，利用干燥、离子凝胶或两者的组合来控制CS的形态和氨基质子化程度。这种方法允许用相同的材​​料成分开发三种不同的功能性 CS 涂层。该方法可有效应用于棉和聚乳酸（PLA）基无纺布，保持基材的渗透性、透气性和机械性能。通过改变加工条件，发现CS涂层可以根据其形态赋予织物不同的功能，例如获得高度疏水性（水接触角达到129°）、广谱抗菌活性（>99.99%）对于通过组合干燥和离子凝胶方法制备的样品。此外，我们的CS涂层织物可以表现出良好的生物相容性，如细胞相容性和组织相容性评估所证明的那样，而CS微球的存在可以在大鼠感染伤口模型中获得优异的抗粘连性能和愈合性能。我们的方法简单且具有潜在的可扩展性，能够对 CS 涂层织物的功能进行模块化控制，以满足不同的要求。 这项工作提供了一种利用 CS 涂层改变织物性能的有前途的策略，使其适用于各种应用，例如面膜、敷料和抗菌纺织品。