npj Digital Medicine ( IF 12.4 ) Pub Date : 2024-06-29 , DOI: 10.1038/s41746-024-01169-7 Claire Garnett 1, 2 , Larisa-Maria Dinu 1 , Melissa Oldham 1 , Olga Perski 3, 4 , Gemma Loebenberg 1 , Emma Beard 1 , Colin Angus 5 , Robyn Burton 6, 7 , Matt Field 8 , Felix Greaves 9, 10 , Matthew Hickman 11 , Eileen Kaner 12 , Susan Michie 13 , Marcus Munafò 2, 14 , Elena Pizzo 15 , Jamie Brown 1
This is a process evaluation of a large UK-based randomised controlled trial (RCT) (n = 5602) evaluating the effectiveness of recommending an alcohol reduction app, Drink Less, compared with usual digital care in reducing alcohol consumption in increasing and higher risk drinkers. The aim was to understand whether participants’ engagement (‘self-reported adherence’) and behavioural characteristics were mechanisms of action underpinning the effectiveness of Drink Less. Self-reported adherence with both digital tools was over 70% (Drink Less: 78.0%, 95% CI = 77.6–78.4; usual digital care: 71.5%, 95% CI = 71.0–71.9). Self-reported adherence to the intervention (average causal mediation effect [ACME] = −0.250, 95% CI = −0.42, −0.11) and self-monitoring behaviour (ACME = −0.235, 95% CI = −0.44, −0.03) both partially mediated the effect of the intervention (versus comparator) on alcohol reduction. Following the recommendation (self-reported adherence) and the tracking (self-monitoring behaviour) feature of the Drink Less app appear to be important mechanisms of action for alcohol reduction among increasing and higher risk drinkers.
中文翻译:
参与和行为机制是否支撑“少喝”应用程序的有效性?
这是对英国一项大型随机对照试验 (RCT) ( n = 5602) 的过程评估,该试验评估了推荐戒酒应用程序 Drink Less 与常规数字护理相比,在减少饮酒风险增加和较高风险者的饮酒量方面的有效性。目的是了解参与者的参与(“自我报告的遵守情况”)和行为特征是否是支撑“少饮”有效性的行动机制。自我报告的两种数字工具的遵守率均超过 70%(少饮酒:78.0%,95% CI = 77.6–78.4;常规数字护理:71.5%,95% CI = 71.0–71.9)。自我报告的干预依从性(平均因果中介效应[ACME] = -0.250,95% CI = -0.42,-0.11)和自我监控行为(ACME = -0.235,95% CI = -0.44,-0.03)两者都部分介导了干预措施(相对于对照组)对酒精减少的影响。遵循“少喝”应用程序的建议(自我报告的遵守情况)和跟踪(自我监控行为)功能似乎是减少饮酒风险增加和较高风险的重要行动机制。