Telomere length (TL) serves as a biomarker of exposure to stressors, including material hardship. Data from the Future of Families and Child Wellbeing Study (1998–2015) were utilized to determine whether prior material hardship was associated with shorter salivary TL at years 9 and 15. 49% of the year 9 study population were female, 49% were Black, and 25% were Hispanic. At year 9 (N = 1990), regression analyses found a significant association between prior material hardship and shorter TL (β = −.005, p < .01). Additionally, at year 15 (N = 1874), material hardship experienced during infancy and toddlerhood was associated with shorter TL (β = −.009, p < .01), pointing toward infancy and toddlerhood as a sensitive period.

中文翻译：

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儿童的物质困难和端粒长度


端粒长度 （TL） 是暴露于压力源（包括物质困难）的生物标志物。来自家庭未来和儿童福祉研究 （1998-2015） 的数据用于确定先前的物质困难是否与 9 岁和 15 岁时较短的唾液 TL 有关。49 年级的研究人群中有 9% 是女性，49% 是黑人，25% 是西班牙裔。在第 9 年 （N = 1990），回归分析发现先前的物质困难与较短的 TL 之间存在显着关联 （β = −.005，p < .01）。 此外，在 15 岁时 （N = 1874），婴儿期和幼儿期经历的物质困难与较短的 TL （β = −.009， p < .01） 相关，表明婴儿期和幼儿期是一个敏感期。