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Prevention and treatment of antibiotics-associated adverse effects through the use of probiotics: A review
Journal of Advanced Research ( IF 11.4 ) Pub Date : 2024-06-04 , DOI: 10.1016/j.jare.2024.06.006
Shuwei Yang 1 , Jiaqi Qiao 1 , Meng Zhang 1 , Lai-Yu Kwok 1 , Bojana Bogovič Matijašić 2 , Heping Zhang 1 , Wenyi Zhang 1
Affiliation  

The human gut hosts a diverse microbial community, essential for maintaining overall health. However, antibiotics, commonly prescribed for infections, can disrupt this delicate balance, leading to antibiotic-associated diarrhea, inflammatory bowel disease, obesity, and even neurological disorders. Recognizing this, probiotics have emerged as a promising strategy to counteract these adverse effects. This review aims to offer a comprehensive overview of the latest evidence concerning the utilization of probiotics in managing antibiotic-associated side effects. Probiotics play a crucial role in preserving gut homeostasis, regulating intestinal function and metabolism, and modulating the host immune system. These mechanisms serve to effectively alleviate antibiotic-associated adverse effects and enhance overall well-being.

中文翻译:


通过使用益生菌预防和治疗抗生素相关不良反应:综述



人类肠道拥有多样化的微生物群落,这对于维持整体健康至关重要。然而,通常用于治疗感染的抗生素可能会破坏这种微妙的平衡,导致抗生素相关性腹泻、炎症性肠病、肥胖,甚至神经系统疾病。认识到这一点,益生菌已成为抵消这些不利影响的一种有前途的策略。本综述旨在全面概述有关利用益生菌控制抗生素相关副作用的最新证据。益生菌在维持肠道稳态、调节肠道功能和代谢以及调节宿主免疫系统方面发挥着至关重要的作用。这些机制有助于有效减轻抗生素相关的不良反应并增强整体健康。
更新日期:2024-06-04
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