Studying the human genome is crucial to embrace precision medicine through tailoring treatment and prevention strategies to the unique genetic makeup and molecular information of individuals. After human genome project (1990–2003) generated the first full sequence of a human genome, there have been concerns towards Northern bias due to underrepresentation of other populations. Multiple countries have now established national genome projects aiming at the genomic knowledge that can be harnessed from their populations, which in turn can serve as a basis for their health care policies in the near future The intention is to introduce the recently established Egypt Genome (EG) to delineate the genomics and genetics of both the modern and Ancient Egyptian populations. Leveraging genomic medicine to improve precision medicine strategies while building a solid foundation for large-scale genomic research capacity is the fundamental focus of EG. EG generated genomic knowledge is predicted to enrich the existing human genome and to expand its diversity by studying the underrepresented African/Middle Eastern populations. The insightful impact of EG goes beyond Egypt and Africa as it fills the knowledge gaps in health and disease genomics towards improved and sustainable genomic-driven healthcare systems for better outcomes. Promoting the integration of genomics into clinical practice and spearheading the implementation of genomic-driven healthcare and precision medicine is therefore a key focus of EG. Mining into the wealth of Ancient Egyptian Genomics to delineate the genetic bridge between the contemporary and Ancient Egyptian populations is another excitingly unique area of EG to realize the global vision of human genome.

中文翻译：

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埃及基因组：迈向非洲新基因组时代


研究人类基因组对于通过根据个体独特的基因组成和分子信息定制治疗和预防策略来实现精准医学至关重要。在人类基因组计划（1990-2003）产生第一个完整的人类基因组序列后，由于其他人群的代表性不足，人们一直担心北方偏见。多个国家现已建立了国家基因组计划，旨在从其人口中获取基因组知识，从而可以作为其近期医疗保健政策的基础。其目的是引入最近建立的埃及基因组（EG） ）描述现代和古埃及人群的基因组学和遗传学。利用基因组医学改进精准医学策略，同时为大规模基因组研究能力奠定坚实的基础是 EG 的根本重点。 EG 生成的基因组知识预计将丰富现有的人类基因组，并通过研究代表性不足的非洲/中东人群来扩大其多样性。 EG 的深刻影响超越了埃及和非洲，因为它填补了健康和疾病基因组学方面的知识空白，以改善和可持续的基因组驱动的医疗保健系统，以获得更好的结果。因此，促进基因组学与临床实践的融合，并带头实施基因组驱动的医疗保健和精准医学是 EG 的重点。挖掘古埃及基因组学的财富来描绘当代和古埃及人群之间的遗传桥梁是 EG 实现人类基因组全球愿景的另一个令人兴奋的独特领域。