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De-clear cell differentiated renal cell carcinoma — a new therapeutic target
Nature Reviews Urology ( IF 12.1 ) Pub Date : 2024-06-27 , DOI: 10.1038/s41585-024-00911-w
Keith A Lawson 1 , W Marston Linehan 1
Affiliation  

Reprogrammed metabolism has been long recognized as a driver of kidney cancer progression, prompting efforts to develop metabolic targeted therapies against this disease. Evidence offers further clarity on the metabolic phenotypes associated with aggressive disease, expanding the potential target space for attacking these tumours at their metabolic roots.

中文翻译:


去透明细胞分化型肾细胞癌——新的治疗靶点



长期以来,重编程的代谢一直被认为是肾癌进展的驱动因素,促使人们努力开发针对这种疾病的代谢靶向疗法。证据进一步阐明了与侵袭性疾病相关的代谢表型,扩大了从代谢根源攻击这些肿瘤的潜在目标空间。
更新日期:2024-06-28
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