Alkenes are fundamental components in synthetic chemistry, extensively used in the production of complex molecules for pharmaceuticals, materials science, and agrochemicals. Nickel-catalyzed transformations of alkenes via nickelacycle intermediates, formed by the oxidative cyclization of alkenes with other π-components on Ni(0), offer a promising approach characterized by high atom and step economy. Although numerous C–C bond formation reactions involving nickelacycles have been widely studied, there is a notable scarcity of comprehensive reviews that focus on transformations of alkenes. Recent progress in ligand design has enhanced control over reactivity and selectivity, enabling a variety of nickel-catalyzed couplings. These include reactions of alkenes with carbon dioxide, isocyanates, alkynes, α,β-unsaturated carbonyls, aldehydes, ketones, and imines. This lack of in-depth discussion highlights the need for a detailed review that encompasses recent advancements in this field. This review summarizes these recent developments in nickel-catalyzed transformations of alkenes via nickelacycles, highlighting the advantages and challenges of this innovative strategy. The goal is to inspire new researchers to explore and contribute to this dynamic field, emphasizing nickelacycle intermediates as versatile tools for effective reactions with various π-components and identifying them as promising avenues for future research.

中文翻译：

---

通过镍环催化烯烃转化


烯烃是合成化学的基本成分，广泛用于生产药物、材料科学和农用化学品的复杂分子。通过烯烃与 Ni(0) 上其他 π 组分的氧化环化形成的镍环中间体进行镍催化烯烃转化，提供了一种具有高原子和步骤经济性的有前景的方法。尽管许多涉及镍环的C-C键形成反应已被广泛研究，但关注烯烃转化的综合综述却明显缺乏。配体设计的最新进展增强了对反应性和选择性的控制，从而实现了各种镍催化偶联。这些包括烯烃与二氧化碳、异氰酸酯、炔烃、α,β-不饱和羰基、醛、酮和亚胺的反应。缺乏深入的讨论凸显了需要对该领域的最新进展进行详细审查。本综述总结了通过镍环进行镍催化烯烃转化的最新进展，强调了这一创新策略的优势和挑战。其目标是激励新的研究人员探索这一充满活力的领域并为其做出贡献，强调镍环中间体作为与各种 π 组分进行有效反应的通用工具，并将其确定为未来研究的有希望的途径。