The HIV epidemic in sub-Saharan Africa displays a varied geographical distribution, with particular regions termed as HIV hotspots due to a higher prevalence of infection. Addressing these hotspots is essential for controlling the epidemic. However, these regions, influenced by historical factors, challenge standard interventions. Legacy effects—the lasting impact of past events—play a substantial role in the persistence of these hotspots. To address this challenge of the standard interventions, we propose a shift towards the UNAIDS 95-95-95 targets. Spatial analysis of HIV viral load and antiretroviral therapy coverage can provide a more comprehensive perspective on the epidemic's dynamics. Studies in Zambia and Zimbabwe, using this approach, have revealed disparities in HIV care metrics across regions. By focusing on the UNAIDS 95-95-95 targets, more effective control strategies can be designed, with consideration of both historical and current factors. This approach would offer a solution-oriented strategy, emphasising tailored interventions based on specific regional needs.

中文翻译：

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从艾滋病毒流行热点转向撒哈拉以南非洲联合国艾滋病规划署 95-95-95 目标的地理空间热点


撒哈拉以南非洲的艾滋病毒流行呈现出不同的地理分布，某些地区由于感染率较高而被称为艾滋病毒热点地区。解决这些热点问题对于控制疫情至关重要。然而，这些地区受历史因素的影响，对标准干预措施提出了挑战。遗留效应——过去事件的持久影响——在这些热点的持续存在中发挥着重要作用。为了应对标准干预措施的这一挑战，我们建议转向联合国艾滋病规划署 95-95-95 目标。 HIV病毒载量和抗逆转录病毒治疗覆盖率的空间分析可以为该流行病的动态提供更全面的视角。赞比亚和津巴布韦使用这种方法进行的研究揭示了各地区艾滋病毒护理指标的差异。通过关注联合国艾滋病规划署的 95-95-95 目标，可以在考虑历史和当前因素的情况下设计更有效的控制策略。这种方法将提供以解决方案为导向的战略，强调根据特定区域需求采取量身定制的干预措施。