The copper‐catalyzed azide alkyne [3+2]‐cycloaddition (CuAAC) reaction of organoboranes represents an attractive area of research within the field of click chemistry, with diverse applications in organic synthesis, medicinal chemistry, or materials science. Despite the potential issues caused by the copper insertion into the carbon‐boron bond, significant progress has been made to harness the reactivity of organoboron compounds in CuAAC. This review provides an overview of the catalytic methods reported for CuAAC with various organoboranes, discussing the stability of the boron group and highlighting recent advancements in this area.

中文翻译：

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铜催化叠氮炔[3+2]-环加成反应有机硼烷的后官能化


有机硼烷的铜催化叠氮炔[3+2]环加成（CuAAC）反应代表了点击化学领域的一个有吸引力的研究领域，在有机合成、药物化学或材料科学中具有多种应用。尽管铜插入碳硼键会带来潜在问题，但在利用 CuAAC 中有机硼化合物的反应性方面已经取得了重大进展。本综述概述了 CuAAC 与各种有机硼烷的催化方法，讨论了硼基团的稳定性并强调了该领域的最新进展。