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Pre-activated macrophage membrane-encased aggregation-induced emission featuring nanoparticles: a novel possibility for tuberculosis treatment
Signal Transduction and Targeted Therapy ( IF 40.8 ) Pub Date : 2024-06-26 , DOI: 10.1038/s41392-024-01855-8 Qiang Cai 1 , Yihao Tian 2 , Quazi T H Shubhra 1, 3
中文翻译：
预激活巨噬细胞膜包裹聚集诱导发射纳米颗粒：结核病治疗的新可能性
更新日期：2024-06-26
Signal Transduction and Targeted Therapy ( IF 40.8 ) Pub Date : 2024-06-26 , DOI: 10.1038/s41392-024-01855-8 Qiang Cai 1 , Yihao Tian 2 , Quazi T H Shubhra 1, 3
Affiliation
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In a recent study published in Nature Nanotechnology, Li et al. introduce the synthesis of a novel photosensitizer with unique aggregation-induced emission (AIE) characteristics.1 They microencapsulated this photosensitizer inside engineered nanoparticles (NPs) coated with pre-activated macrophage cell membranes (CMs), an innovative approach marking a significant leap in nanomedicine by offering a pathway to potent tuberculosis (TB) treatments that bypass antibiotic resistance with unparalleled precision.
中文翻译：
预激活巨噬细胞膜包裹聚集诱导发射纳米颗粒：结核病治疗的新可能性
在最近发表在《自然纳米技术》上的一项研究中，Li 等人。介绍了一种具有独特聚集诱导发射（AIE）特性的新型光敏剂的合成。 1他们将这种光敏剂微囊化在涂有预激活巨噬细胞膜 (CM) 的工程纳米颗粒 (NP) 内，这是一种创新方法，标志着纳米医学的重大飞跃，提供了一条以无与伦比的精度绕过抗生素耐药性的有效结核病 (TB) 治疗途径。
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