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Green synthesis of glutaramides, piperidino[1,2-a]benzimidazol-1-ones and N-cyclopentenyl benzimidazolones enabled by microwave assisted domino reactions of cyclic 2-diazo-1,3-diketones with aniline derivatives
Organic Chemistry Frontiers ( IF 4.6 ) Pub Date : 2024-06-26 , DOI: 10.1039/d4qo00613e
Cheng Zhao , Xiao-Wei Hu , Yi-Bing Xu , Xiong-Wei Liu , You-Ping Tian , Yun-Lin Liu

Microwave-assisted divergent domino reactions between cyclic 2-diazo-1,3-diketones and aniline derivatives selectively leading to either glutaramides, piperidino[1,2-a]benzimidazol-1-ones or N-cyclopentenyl benzimidazolones are described. This synthetic protocol features easy operation, a short reaction time, and environmental friendliness.

中文翻译:


通过环2-重氮-1,3-二酮与苯胺衍生物的微波辅助多米诺反应实现戊二酰胺、哌啶基[1,2-a]苯并咪唑-1-酮和N-环戊烯基苯并咪唑酮的绿色合成



描述了环状2-重氮-1,3-二酮和苯胺衍生物之间的微波辅助发散多米诺反应,选择性地产生戊二酰胺、哌啶基[1,2-a]苯并咪唑-1-酮或N-环戊烯基苯并咪唑酮。该合成方案具有操作简单、反应时间短、环境友好等特点。
更新日期:2024-06-26
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