ObjectiveTo histomorphometrically determine the effects of hard‐ and/or soft‐tissue augmentation by applying the early implant placement protocol.Materials and MethodsThe distal roots of the maxillary second and third premolars were extracted in 10 mongrel dogs. After 1 month, early implant placement was performed in the distal roots, resulting in buccal dehiscence defects. Four treatments were then randomly applied: (1) guided bone regeneration (GBR), (2) connective tissue grafting (CTG), (3) simultaneous GBR and CTG (GBR + CTG) and (4) no further treatment (control). Healing abutments were connected to all implants to allow non‐submerged healing. At 4 and 16 weeks, tissue sections were harvested and histomorphometric analyses were performed.ResultsGroup GBR presented the largest total tissue thickness at 4 weeks, but underwent a greater remodelling compared with the other groups between 4 and 16 weeks. At 16 weeks, the overall tissue thickness was largest in group GBR + CTG. This group was also the most favourable in terms of the level of the margo mucosae and the presence of mineralized tissue at the coronal level. Group CTG demonstrated a stable tissue thickness over time, with a larger thickness at 16 weeks compared with group GBR.ConclusionSimultaneous CTG and GBR resulted in the most‐favourable tissue thickness when applying the early implant placement protocol.

中文翻译：

---

早期种植体植入硬组织和/或软组织移植的影响：犬科动物探索性研究的组织形态学结果


目的通过应用早期种植体植入方案，通过组织形态学确定硬组织和/或软组织增强的效果。材料与方法提取 10 只犬上颌第二、第三前磨牙远端根。1 个月后，在远端根部进行早期种植体植入，导致颊裂缺损。然后随机应用四种处理：（1） 引导骨再生 （GBR），（2） 结缔组织移植 （CTG），（3） 同时 GBR 和 CTG （GBR + CTG） 和 （4） 无需进一步治疗（对照）。愈合基台连接到所有种植体，以实现非浸没愈合。在 4 周和 16 周时，收获组织切片并进行组织形态学分析。结果GBR 组在 4 周时呈现出最大的总组织厚度，但在 4 至 16 周之间与其他组相比，重塑程度更大。16 周时，GBR + CTG 组总组织厚度最大。就 margo 粘膜水平和冠状水平矿化组织的存在而言，该组也是最有利的。CTG 组随着时间的推移表现出稳定的组织厚度，与 GBR 组相比，16 周时的厚度更大。结论在应用早期种植体植入方案时，同时 CTG 和 GBR 导致最有利的组织厚度。