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Development of a model for the ethanol concentration limit as a function of temperature and initial substrate concentration using the yeast Saccharomyces cerevisiae
Biotechnology and Bioengineering ( IF 3.5 ) Pub Date : 2024-06-22 , DOI: 10.1002/bit.28771 Ruan Dionízio SILVA 1 , Flávio Luiz Honorato da Silva 1 , Sharline Florentino de Melo Santos 1 , Alberto Brandão Torres Neto 1 , Julice Dutra Lopes 1 , Josilene de Assis Cavalcante 1
Biotechnology and Bioengineering ( IF 3.5 ) Pub Date : 2024-06-22 , DOI: 10.1002/bit.28771 Ruan Dionízio SILVA 1 , Flávio Luiz Honorato da Silva 1 , Sharline Florentino de Melo Santos 1 , Alberto Brandão Torres Neto 1 , Julice Dutra Lopes 1 , Josilene de Assis Cavalcante 1
Affiliation
In this study, a model was developed to simulate the effect of temperature ( ) and initial substrate concentration ( ) on the ethanol concentration limit ( ) using the yeast Saccharomyces cerevisiae. To achieve this, regressions were performed using data provided by other authors for to establish a model dependent on and capable of predicting results with statistical significance. After constructing the model, a response surface was generated to determine the conditions where reaches higher values: temperatures between 28°C and 32°C and an initial substrate concentration around 200 g/L. Thus, the proposed model is consistent with the observations that increasing temperatures decrease the ethanol concentration obtained, and substrate concentrations above 200 g/L lead to a reduction in ethanol concentration even at low temperatures such as 28°C.
中文翻译:
使用酿酒酵母开发乙醇浓度极限随温度和初始底物浓度变化的模型
在这项研究中,开发了一个模型来模拟温度的影响( )和初始底物浓度( )对乙醇浓度限值( )使用酿酒酵母。 为了实现这一目标,使用其他作者提供的数据进行回归建立一个模型依赖于和能够预测具有统计显着性的结果。 构建模型后,生成响应面以确定其中的条件达到更高的值:温度在 28°C 至 32°C 之间,初始底物浓度约为 200 g/L。因此,所提出的模型与观察结果一致,即升高温度会降低获得的乙醇浓度,并且即使在 28°C 等低温下,底物浓度高于 200 g/L 也会导致乙醇浓度降低。
更新日期:2024-06-22
中文翻译:
使用酿酒酵母开发乙醇浓度极限随温度和初始底物浓度变化的模型
在这项研究中,开发了一个模型来模拟温度的影响( )和初始底物浓度( )对乙醇浓度限值( )使用酿酒酵母。 为了实现这一目标,使用其他作者提供的数据进行回归建立一个模型依赖于和能够预测具有统计显着性的结果。 构建模型后,生成响应面以确定其中的条件达到更高的值:温度在 28°C 至 32°C 之间,初始底物浓度约为 200 g/L。因此,所提出的模型与观察结果一致,即升高温度会降低获得的乙醇浓度,并且即使在 28°C 等低温下,底物浓度高于 200 g/L 也会导致乙醇浓度降低。