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An Electroencephalogram Signature of Melanin-Concentrating Hormone Neuron Activities Predicts Cocaine Seeking
Biological Psychiatry ( IF 9.6 ) Pub Date : 2024-04-26 , DOI: 10.1016/j.biopsych.2024.04.009
Yao Wang 1 , Danyang Li 2 , Joseph Widjaja 3 , Rong Guo 4 , Li Cai 4 , Rongzhen Yan 4 , Sahin Ozsoy 5 , Giancarlo Allocca 6 , Jidong Fang 7 , Yan Dong 8 , George C Tseng 2 , Chengcheng Huang 8 , Yanhua H Huang 4
Affiliation  

Identifying biomarkers that predict substance use disorder propensity may better strategize antiaddiction treatment. Melanin-concentrating hormone (MCH) neurons in the lateral hypothalamus critically mediate interactions between sleep and substance use; however, their activities are largely obscured in surface electroencephalogram (EEG) measures, hindering the development of biomarkers.

中文翻译:


黑素浓缩激素神经元活动的脑电图特征可预测可卡因的寻找



识别预测物质使用障碍倾向的生物标志物可以更好地制定抗成瘾治疗策略。下丘脑外侧的黑色素浓缩激素 (MCH) 神经元关键介导睡眠和物质使用之间的相互作用;然而,它们的活性在表面脑电图 (EEG) 测量中在很大程度上被掩盖,阻碍了生物标志物的发展。
更新日期:2024-04-26
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