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All roads lead to OSBP
Nature Chemical Biology ( IF 12.9 ) Pub Date : 2024-06-21 , DOI: 10.1038/s41589-024-01639-9
Po-Hsun Brian Chen , Jeremy M. Baskin

Natural products and synthetic bifunctional molecules enable the development of new chemical probes that target oxysterol-binding protein (OSBP), a key player in intracellular cholesterol homeostasis and Golgi complex integrity and a potential target for metabolic disease and cancer.

中文翻译:


条条大路通OSBP



天然产物和合成双功能分子能够开发针对氧甾醇结合蛋白(OSBP)的新型化学探针,氧甾醇结合蛋白是细胞内胆固醇稳态和高尔基复合体完整性的关键参与者,也是代谢疾病和癌症的潜在靶点。
更新日期:2024-06-21
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