Antimicrobial resistance (AMR) is a global public health threat, and the environment has been identified as an important reservoir for resistant microorganisms and genes. Storm overflows (SOs) discharge wastewater and stormwater, and are found throughout many wastewater networks. While there are no data currently showing the impact of SOs on the environment with respect to AMR in the UK, there is a small but growing body of evidence globally highlighting the potential role of SOs on environmental AMR. This review aims to provide an overview of the current state of SOs, describe global data investigating the impact of SOs on environmental AMR, and discuss the implications of SOs regarding AMR and human health. In addition, the complexities of studying the effects of SOs are discussed and a set of priority research questions and policy interventions to tackle a potentially emerging threat to public health are presented.

中文翻译：

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风暴溢流是否会影响环境中的抗菌素耐药性？这与人类健康相关吗？英国对全球问题的看法


抗生素耐药性（AMR）是一个全球性的公共卫生威胁，环境已被确定为耐药微生物和基因的重要储存库。风暴溢流 (SO) 排放废水和雨水，在许多废水管网中都存在这种现象。虽然英国目前没有数据显示 SO 对环境的抗菌素耐药性影响，但全球范围内有少量但不断增长的证据强调 SO 对环境抗菌素耐药性的潜在作用。本综述旨在概述SOs的现状，描述调查SOs对环境AMR影响的全球数据，并讨论SOs对AMR和人类健康的影响。此外，还讨论了研究 SO 影响的复杂性，并提出了一系列优先研究问题和政策干预措施，以应对潜在的公共卫生威胁。